Table 1.
Demographic and clinical characteristics
| Variables | Subjects (n = 61) | Indeterminate form (n = 17) |
Cardiac form without ventricular dysfunction (n = 16) | Cardiac form with ventricular dysfunction (n = 28) |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age (years), mean ± standard deviation | 58 ± 8 | 59 ± 11 | 59 ± 9 | 58 ± 7 |
| Female, n (%) | 36 (59) | 12 (70) | 12 (75) | 12 (43) |
| Lived in a mud house, n (%) | 50 (82) | 15 (88) | 15 (94) | 20 (71) |
| Family members with positive serology, n (%) | 39 (64) | 11 (65) | 14 (88) | 14 (50) |
| Digestive form, n (%) | 4 (6.6) | - | 2 (12) | 2 (7) |
| Body mass index (kg/m2), mean ± standard deviation | 25 ± 4 | 26 ± 4 | 27 ± 4 | 26 ± 3 |
| Comorbidities, n (%) | ||||
| Arterial hypertension | 44 (72) | 14 (82) | 12 (75) | 18 (64) |
| Diabetes mellitus | 9 (15) | 4 (23) | - | 5 (18) |
| Syncope | 6 (7) | 1 (6) | 1 (6) | 2 (7) |
| Smoking | 16 (26) | 3 (18) | 3 (18) | 10 (36) |
| Congestive heart failure NYHA III/IV | 16 (26) | - | - | 16 (57)* |
| Laboratory characteristics | ||||
| Creatinine (mg/dL) | 0.88 (0.7 - 0.99) | 0.84 (0.7 - 0.98) | 0.78 (0.6 - 0.91) | 0.94 (0.7 - 1.0) |
| Sodium (mmoL/dL) | 140 ± 3 | 138 ± 2 | 139 ± 2 | 139 ± 2 |
| Hemoglobin (g/dL) | 13.9 ± 0.9 | 14.2 ± 1.3 | 13.4 ± 0.7 | 14.2 ± 1.0 |
| Total Cholesterol (mg/dL) | 193 ± 38 | 202 ± 40 | 194 ± 42 | 200 ± 45 |
| Reactive C protein (mg/dL) | 1.15 (0.63 - 4.02) | 1.71 (0.35 - 6.54) | 1.24 (0.51 - 4.74) | 1.09 (0.73 - 3.62) |
| NT-ProBNP (pg/mL) | 686 (66 - 816) | 60.5 (34 - 108) | 96.0 (73 - 181) | 839.5** (189 - 2271) |
| Troponin I (ng/mL) | 0.684 (0.012 - 0.04) | 0.012 (0.012 - 0.012) | 0.012 (0.012 - 0.028) | 0.038 (0.019 - 0.06) |
| LVEF (%) | 54 ± 15 | 64 ± 3 | 64 ± 4 | 43 ± 10* |
| METS | 9 ± 2.5 | 12 ± 3 | 9 ± 2 | 8 ± 2 |
NYHA: New York Heart Association; NT-ProBNP: N-terminal pro B-type natriuretic peptide; LVEF: left ventricular ejection fraction; METS: metabolic equivalent of task. Data expressed as mean ± standard deviation or percentage (%) for discrete variables and median and interquartile range for continuous variables with non-normal distribution.
*
p < 0.001, Fisher's exact text.
**
p < 0.001, Kruskal-Wallis one-way analysis of variance.