Table 2.
Characteristics of the indeterminate form versus the cardiac form without left ventricular dysfunction
| Variables | Indeterminate form (n = 17) | Cardiac form without ventricular dysfunction (n = 16) | p value |
|---|---|---|---|
| Rassi Score | 2 (0 - 2) | 6 (1 - 8) | 0.30‡ |
| Area of fibrosis from the CMR (%) | 4.1 (2.1 - 10.7) | 2.3 (1 - 5) | 0.18‡ |
| LV ejection fraction (%) | 72 ± 8 | 67 ± 6 | 0.09† |
| Ventricular Tachycardia (%) | - | 20 | 0.001* |
| METS | 10 ± 3 | 9.4 ± 2 | 0.60† |
| Maximum VO2 | 35 ± 10 | 33 ± 7 | 0.47† |
| NT-ProBNP (pg/mL) | 125 (34 - 108) | 171 (73 - 181) | 0.61‡ |
| Ultrasensitive PCR (mg/L) | 1.7 (0.35 - 6.5) | 1.2 (0.51 - 4.7) | 0.40‡ |
| Troponin I (ng/mL) | 0.012 (0.0 - 0.012) | 0.012 (0.012 - 0.028) | 0.31‡ |
| IL-2 (pg/mL) | 0.21 (0.03 - 0.55) | 0.27 (0.03 - 0.96) | 0.14‡ |
| IL-4 (pg/mL) | 0.62 (0.00 - 1.6) | 0.37 (0.2 - 2.2) | 0.83‡ |
| IL-6 (pg/mL) | 2.26 (1.39 - 4.35) | 3.98 (2.01 - 6.22) | 0.50‡ |
| IL-10 (pg/mL) | 0.44 (0.19 - 1.06) | 0.63 (0.50 - 1.61) | 1.47‡ |
| TNF-alfa (pg/mL) | 0.48 (0.14 - 1.15) | 0.72 (0.58 - 2.71) | 1.16‡ |
| IFN-gama (pg/mL) | 2.07 (1.30 - 4.35) | 2.15 (1.69 - 6.73) | 0.51‡ |
CMR: cardiac magnetic resonance; LV: left ventricular; METS: metabolic equivalent of task; Maximum VO2: Maximum Oxygen volume; NT-ProBNP: N-terminal pro B-type natriuretic peptide.
*
Fisher's exact test;
†
Student's t test;
‡
Mann-Whitney's test. Data expressed as mean ± standard deviation or percentage (%) for discrete variables and median and interquartile range for continuous variables with non-normal distribution.