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. 2018 Apr;24(4):486–498. doi: 10.1261/rna.062703.117

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© 2018 Zhang et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 4. — TAT-BIND suppressed retinal degeneration in DsRed_CAG100 Drosophila in a dose-dependent manner. (A) TAT-BIND suppressed retinal degeneration in DsRed_CAG100 Drosophila. (B) Statistical analysis of panel A. (C) Dose-response effect of TAT-BIND on suppressing eye degeneration in DsRed_CAG100 Drosophila. (D) Statistical analysis of panel C. Third instar larvae were treated with respective peptides dissolved in 2% sucrose solution for 2 h at room temperature. Pseudopupil assay was performed on 12-d-old adult flies. The genotypes of the flies were: w; gmr-GAL4 UAS-DsRed_CAG0/+; +/+ and w; gmr-GAL4/+; UAS-DsRed_CAG100/+. Data are plotted as mean ± SEM and were collected from at least three independent experiments. (*) P < 0.05, (**) P < 0.01, (***) P < 0.001. NS, no significant difference.