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. 2001 Sep 4;98(19):10833–10838. doi: 10.1073/pnas.191208598

Figure 1.

Figure 1

SAHA-induced cell death was not mediated by death receptors. CEM cells expressing sense (CEM-CrmA) or antisense (CEM-CrmA/AS) CrmA cDNA were treated for 24 hr with 0–5 μM SAHA or 12 hr with 100 ng/ml anti-Fas antibody clone CH-11; cell death was assessed by trypan blue. The results shown are representative of three experiments with a number of different CEM-CrmA and CEM-CrmA/AS cell lines. For all cell-death assays, statistical differences (P < 0.05 as determined by the Mann–Whitney U test) between samples are denoted by *.