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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Biologicals. 2017 Sep 29;50:27–34. doi: 10.1016/j.biologicals.2017.09.005

Fig. 5. Superposition of the four independent paratopes in 5K8A.

Fig. 5

along with five high-resolution precedent structures from the PDB (2VXV, 2XzA, 3N9G, 3NTC, and 4M5Y). The cores of the six CDR loops are shown in blue, green and red. Apart from the CDR loops, the mainchain conformations are all well conserved. In the CDR loops, the four structures in 5K8A are also very similar. In the CDR loops, the five precedents have not only different sequence, but different lengths, so their conformations show large variations. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)