Table 4.
PDA vesicles for detection of viruses.
Composition of the Bilayer | Diameter of Vesicles | Type of Transduction | Type of Virus | Virus LOD | Reference |
---|---|---|---|---|---|
95% PCDA/5% sialic acid derivatized PCDA | colorimetry | Influenza | 11 × 107 virus particles | [55] | |
95% PCDA/5% sialic acid derivatized PCDA | colorimetry | Influenza | 8 × 107 virus particles | [56] | |
PCDA/5% S-sialo PCDA | colorimetry | Influenza X-31 | 0.78 HAU | [57] | |
PDMA/DMPC/G1/G2 G1: sialic acid-β-glucoside G2: lactose-β-glucoside |
10–20 nm | colorimetry | H5N1 Avian influenza | 10 ng/mL hemagglutinin | [58] |
PCDA Anti-H5N1 monoclonal antibody grafted on vesicle surface |
117 nm | colorimetry fluorescence |
H5N1 Avian influenza | 30 ng/mL HAQ 1 ng/mL HAQ |
[59] |
PCDA/DMPC Anti-HA monoclonal antibody grafted on vesicle surface |
colorimetry | H5 influenza | 0.53 copies/µL | [60] | |
PEP-PCDA | ~50 nm | colorimetry | H1N1 influenza | 105 PFU | [61] |
DMPC: dimyristoylphosphatidylcholine; HAQ: target antigen of H5N1 Avian influenza virus strain; LOD: limit of detection; PCDA: 10,12-pentacosadiynoic acid; PEP-PCDA: peptide-functionalized 10,12-pentacosadiynoic acid.