Table 1.
Association of SPP1 expression with clinicopathologic characteristics in 55 patients of EOC
| Characteristics | No of patients (N=55) | SPP1 expression
|
p-value | |
|---|---|---|---|---|
| Low no (%) | High no (%) | |||
| Age (years) | ||||
| <50 | 24 | 9 (37.50) | 15 (62.50) | >0.05 |
| ≥50 | 31 | 11 (35.48) | 20 (64.52) | |
| Normal ovarian | 10 | 8 (80.00) | 2 (20.00) | <0.05 |
| Cancer tissues | 45 | 12 (36.67) | 33 (73.33) | |
| FIGO stage | ||||
| I/II | 23 | 10 (43.48) | 13 (56.52) | <0.05 |
| III/IV | 22 | 2 (9.09) | 20 (90.91) | |
| Grade | ||||
| 1 | 12 | 5 (41.67) | 7 (58.33) | <0.05 |
| 2 | 14 | 4 (28.57) | 10 (71.43) | |
| 3 | 19 | 3 (15.79) | 16 (84.21) | |
| Grade 2–3 versus 1 | ||||
Abbreviations: SPP1, secreted phosphoprotein 1; EOC, epithelial ovarian cancer; FIGO, International Federation of Gynecology and Obstetrics.