. Author manuscript; available in PMC: 2018 Mar 16.

Published in final edited form as: Diabetologia. 2016 Oct 4;60(1):43–49. doi: 10.1007/s00125-016-4122-1

Table 5.

Summary of results from sensitivity analyses: posterior PPBE using models from each source publication (i.e. differing outcome and explanatory variables)

Source publication	Outcome	Explanatory variables used in source publication	Prior information used	Dose information	Posterior PPBE (%)
Ludvigsson (2008) [4]	C-peptide change (15 months)	Treatment baseline C-peptide	Normal distribution	Two-dose	85.88
Ludvigsson (2008) [4]	C-peptide change (30 months)	Treatment baseline C-peptide	Normal distribution	Two-dose	97.63
Ludvigsson (2008) [4]	AUC change (15 months)	Treatment baseline AUC	Normal distribution	Two-dose	99.38
Ludvigsson (2008) [4]	AUC change (30 months)	Treatment baseline AUC	Normal distribution	Two-dose	98.16
Wherrett (2011) [5]	log_e (C-peptide + 1) (12 months)	Sex	Normal distribution	Two-dose	26.76
		Age		Three-dose	68.82
		Treatment
		Baseline log_e (C-peptide + 1)
Ludvigsson (2012) [6]	log_e (AUC/initial AUC) (3, 9 and 15 months)	Treatment	Normal distribution	Two-dose	97.14
		log_e (initial AUC)		Four-dose	96.82
		Month
		Treatment × month
		log_e (Initial AUC) × month