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. 2018 Mar 15;13:40. doi: 10.1186/s13023-018-0779-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Combined log R ratio (LRR) plots of the 17p11.2 copy number variation (CNV) regions. a The panel shows a genome level LRR plot. b The panel shows the plot for chromosome 17. c The panel shows a detailed view of a CNV region in chromosome 17. Low values of LRR (less than − 1) indicate a deletion in the region of chromosome 17. MAD, median absolute deviation