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. 2018 Mar 13;13:1483–1493. doi: 10.2147/IJN.S157293

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© 2018 Salimi et al. This work is published and licensed by Dove Medical Press Limited

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Blood chemistry of (A) blood factors, (B) renal factors, and (C) hepatic factors of animals treated with 10, 5, 1, 0.5, and 0 (control) mg/kg of G₄@IONPs. No significant difference was observed in blood and renal parameters. A significant increase of direct bilirubin was detected in a group of 10 mg/kg (*P<0.05).

Abbreviations: IONPs, iron oxide nanoparticles; Hgb, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; BUN, blood urea nitrogen; Cr, creatine; Glu, glucose; ALP, alkaline phosphatase; ALB, albumin; NPs, nanoparticles.