Table 1.
OLIG expression in normal and neoplastic brain
| Clinical diagnosis | mRNA expression level
|
|
|---|---|---|
| OLIG1 | OLIG2 | |
| Nonneoplastic brain | ||
| Cerebral cortex | +/− | +/− |
| White matter | + | + |
| Brain tumors | ||
| Oligodendrogliomas | ||
| Oligodendroglioma (grade II) | +++++ | +++++ |
| Oligodendroglioma (grade II) | ++++ | ++++ |
| Oligodendroglioma (grade II) | ++++ | ++++ |
| Anaplastic oligodendroglioma (grade III) | +++++ | +++++ |
| Anaplastic oligodendroglioma (grade III) | ++++ | ++++ |
| Anaplastic oligodendroglioma (grade III) | +++ | +++ |
| Astrocytomas | ||
| Pilocytic astrocytoma (grade I) | +/− | +/− |
| Pilocytic astrocytoma (grade I) | +/− | +/− |
| Astrocytoma (grade II) | +/− | +/− |
| Astrocytoma (grade II) | +/− | +/− |
| Astrocytoma (grade II) | +/− | +/− |
| Astrocytoma (grade II) | +/− | +/− |
| Astrocytoma (grade II) | + | + |
| Anaplastic astrocytoma (grade III) | +/− | +/− |
| Anaplastic astrocytoma (grade III) | +/− | +/− |
| Glioblastomas | ||
| Glioblastoma (grade IV) | +/− | +/− |
| Glioblastoma (grade IV) | +/− | +/− |
| Glioblastoma (grade IV) | + | + |
| Glioblastoma (grade IV) | + | + |
| Glioblastoma (grade IV) | + | + |
| Glioblastoma (grade IV) | + | + |
| Glioblastoma (grade IV) | ++ | ++ |
| Glioblastoma (grade IV) | ++ | ++ |