Table 5.

Questionnaire items included in the final model

Item	Question
1	How well does the subject’s quick relief inhaler (rescue inhaler) provide symptom relief?
2	How often does the subject need to keep a rescue inhaler with him/her?
4	In the past two years has the subject had periods of several weeks or longer where (s)he had no respiratory symptoms?
8	On average, how much do the subject’s good and bad days differ?
10	When the subject’s respiratory symptoms are bad, how long until they return to normal?
12	How many members of the subject’s immediate biological family have had asthma, nasal allergies or eczema?
18	If the subject stops taking his/her regular (maintenance/controller) respiratory medications, how do his/her respiratory symptoms change?
29	In the past 12 months, how frequently has the subject experienced breathlessness?
35	How often would the subject describe themselves as feeling depressed?

Note: Age, sex, smoking status, body mass index, and exacerbation history were also included in the final model.