Table 2.

Most appropriate reperfusion strategy by time from symptom onset and anticipated treatment delays

Treatment delay	Time from symptom onset
	< 2 h	2–3 h	3–6 h*
< 60 min	Primary PCI	Primary PCI or fibrinolysis†	Primary PCI
60–120 min	Fibrinolysis†	Primary PCI or fibrinolysis†	Primary PCI
> 120 min	Fibrinolysis†	Fibrinolysis†	Fibrinolysis†

Patients with higher risk, including those with Killip class > 1, may benefit from primary PCI even when there are treatment delays up to 120 min

PCI percutaneous coronary intervention

*If time from symptom onset is greater than 6 h, primary PCI is appropriate regardless of treatment delay

^†In case of fibrinolytic therapy, immediate transfer to a PCI center after fibrinolysis should be considered for cardiac angiography within 3 to 24 h