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. 2001 Sep 11;98(19):10857–10862. doi: 10.1073/pnas.191117498

Figure 4.

Figure 4

Leukemic cell engraftment (%) in the bone marrow of normal (noninoculated) and HL-60 inoculated NOD-SCID mice. HL-60-injected mice had a 2-fold increase in the number of Flk-1-positive cells, compared with normal mice, reflecting an increase in bone marrow angiogenesis after leukemia inoculation. DC101-, IMC-1C11-, and DC101 + IMC-1C11-treated mice had a significantly lower percentage of human cells in the bone marrow than untreated mice (P < 0.001).