Table 1. Details of analytical validation experiments performed to assess sensitivity of the eTAm-Seq technology, including range of input DNA (AC), AF (%), number of sample repeats per operator, and number of operators per laboratory.
| Input DNA (AC) | AF (%)* | Number of repeats/operator | Number of operators/laboratory |
|---|---|---|---|
| 16,000 | 0.25%-0.33% | 4 | 3 |
| 8,000 | 1%-1.3% | 3 | 3 |
| 2,000 | 2%-2.5% | 7 | 3 |
| 8,000 | 0.5%-0.65% | 3 | 3 |
| 8,000 | 0.25%-0.33% | 3 | 3 |
| 8,000 | 0.13%-0.16% | 3 | 3 |
| 8,000 | 0.06%-0.08% | 3 | 3 |
* AF shows indicative ranges for Tru-Q reference material, full list of values presented in S4 Table.