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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Mol Cell Cardiol. 2017 Dec 30;115:94–103. doi: 10.1016/j.yjmcc.2017.12.014

Figure 6. Angiotensin II infusion promotes remodeling of the mitral valve tissue in mice which can be partially blocked by 5HTR2B inhibition.

Figure 6

(A) Representative H&E and (B) Modified Movat Pentachrome staining of cross sections of MV from mice hearts harvested 28 days after saline or Ang II chronic infusion with or without treatment of 10 μM LY 272015 (Magnification 20x). (C) Quantitative analysis of the average MV leaflet section area for each treatment group +/− SE. *p<0.008; **p<0.002. (D) Representative H&E of MV from mice hearts harvested 28 days after saline or Ang II chronic infusion with or without treatment Terguride or Ketansarin. (E) Quantitative analysis of the average MV leaflet section area for each treatment group indicated in D +/− SE. *p<0.002.