Table 1.
NHSII (1989) | WHS (1993–1996) | |||
---|---|---|---|---|
No migraine (N=96,138, 85%) |
Migraine (N=16,986, 15%) |
No migraine (N=27,476, 82%) |
Migraine (N=6014, 18%) |
|
Mean (SD) | ||||
Age | 34.6 (4.7) | 35.5 (4.5) | 54.6 (7.1) | 53.3 (6.4) |
BMI (kg/m2) | 24.0 (4.9) | 24.6 (5.3) | 25.9 (5.0) | 26.1 (5.1) |
Percent | ||||
Family history of breast or ovarian cancer | 7.2 | 7.6 | 8.2 | 8.4 |
Oral contraceptive use (NHS) | ||||
Never | 17.3 | 13.7 | -- | -- |
<1 year | 12.7 | 14.1 | -- | -- |
1–<5 years | 38.4 | 39.6 | -- | -- |
5–<10 years | 23.6 | 24.1 | -- | -- |
10+ years | 8.0 | 8.4 | -- | -- |
Oral contraceptive use (WHS) | ||||
Never | -- | -- | 31.6 | 26.2 |
<0.5 year | -- | -- | 9.2 | 10.7 |
0.5–2 years | -- | -- | 19.2 | 23.1 |
3–4 years | -- | -- | 14.7 | 14.8 |
5+ years | -- | -- | 25.3 | 25.2 |
Parity | ||||
Nulliparous | 29.5 | 25.5 | 12.9 | 12.2 |
1 child | 19.1 | 18.9 | 9.0 | 9.6 |
2 children | 32.9 | 35.2 | 29.6 | 29.9 |
3 children | 14.3 | 15.6 | 24.1 | 24.8 |
4+ children | 4.3 | 4.8 | 24.4 | 23.5 |
Alcohol use | ||||
None | 37.0 | 39.5 | 43.7 | 46.3 |
0.1–<5 grams/day | 42.6 | 43.4 | 31.7 | 33.8 |
5+ grams/day | 20.4 | 17.2 | 24.6 | 19.9 |
Smoking status | ||||
Never | 66.0 | 62.4 | 50.6 | 53.9 |
Past | 21.0 | 22.8 | 36.3 | 34.0 |
Current | 13.0 | 14.9 | 13.1 | 12.1 |
NSAID use | ||||
Never | 75.2 | 57.4 | 89.0 | 84.3 |
Past | -- | -- | -- | -- |
Current | 24.8 | 42.6 | 11.0 | 15.7 |
Tubal ligation | 15.0 | 19.4 | 16.8 | 17.9 |
Hysterectomy | 3.0 | 6.6 | 20.8 | 25.5 |
Unilateral oophorectomy | 0.7 | 1.6 | 5.4 | 6.5 |
Menopausal status | ||||
Premenopausal | 99.0 | 98.7 | 32.3 | 34.1 |
Postmenopausal | 0.4 | 0.5 | 47.0 | 39.2 |
Unknown | 0.6 | 0.8 | 20.5 | 26.5 |
HT use* | ||||
E ever use | 4.7 | 9.6 | 11.2 | 13.9 |
E+P ever use | 40.2 | 39.8 | 18.6 | 18.1 |
Other HT ever use | 15.5 | 20.5 | 13.6 | 15.6 |
Postmenopausal only