Table 1.
Characteristics of Combined TX and NY Matched Cohorts by Aggregated Ages of Exposure
| >Birth – ≤6 m | >6 m – ≤1 yr | >1 yr – ≤2 yr | >2 yr – ≤3 yr | >3 yr – ≤4 yr | >4 yr – ≤5 yr | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||||||
| Exposure | Exposure | Exposure | Exposure | Exposure | Exposure | ||||||||
| No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | ||
| n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | ||
| Sex |
Female
|
6292 (12.4) | 1288 (12.7) | 1366 (7.2) | 271 (7.2) | 7628 (20) | 1497 (19.6) | 10191 (31.5) | 2062 (31.9) | 11368 (38.8) | 2281 (38.9) | 9788 (42.9) | 1957 (42.9) |
| Male | 44633 (87.6) | 8897 (87.4) | 17529 (92.8) | 3508 (92.8) | 30552 (80) | 6139 (80.4) | 22184 (68.5) | 4413 (68.2) | 17927 (61.2) | 3578 (61.1) | 13007 (57.1) | 2602 (57.1) | |
|
| |||||||||||||
| Race |
White
|
14069 (27.6) | 2854 (28) | 5235 (27.7) | 1035 (27.4) | 11573 (30.3) | 2305 (30.2) | 9930 (30.7) | 1993 (30.8) | 8389 (28.6) | 1649 (28.1) | 6613 (29) | 1319 (28.9) |
|
Black
|
10134 (19.9) | 1949 (19.1) | 5948 (31.5) | 1125 (29.8) | 9292 (24.3) | 1847 (24.2) | 5854 (18.1) | 1165 (18) | 4348 (14.8) | 902 (15.4) | 3309 (14.5) | 672 (14.7) | |
|
Hispanic
|
21550 (42.3) | 4346 (42.7) | 5700 (30.2) | 1193 (31.6) | 13396 (35.1) | 2679 (35.1) | 13905 (43) | 2761 (42.6) | 14248 (48.6) | 2839 (48.5) | 11363 (49.9) | 2251 (49.4) | |
| Other | 5172 (10.2) | 1036 (10.2) | 2012 (10.7) | 426 (11.3) | 3919 (10.3) | 805 (10.5) | 2686 (8.3) | 556 (8.6) | 2310 (7.9) | 469 (8) | 1510 (6.6) | 317 (7) | |
|
| |||||||||||||
| Income based on ZIP code of residence (Quartile) |
Quartile 1
|
13368 (26.3) | 2688 (26.4) | 5022 (26.6) | 1000 (26.5) | 10725 (28.1) | 2111 (27.7) | 9158 (28.3) | 1800 (27.8) | 8455 (28.9) | 1666 (28.4) | 6501 (28.5) | 1293 (28.4) |
|
Quartile 2
|
13056 (25.6) | 2612 (25.7) | 4503 (23.8) | 917 (24.3) | 9998 (26.2) | 1993 (26.1) | 8649 (26.7) | 1718 (26.5) | 7894 (27) | 1597 (27.3) | 6397 (28.1) | 1290 (28.3) | |
|
Quartile 3
|
12236 (24) | 2437 (23.9) | 4568 (24.2) | 904 (23.9) | 9213 (24.1) | 1863 (24.4) | 7974 (24.6) | 1600 (24.7) | 7132 (24.4) | 1402 (23.9) | 5759 (25.3) | 1141 (25) | |
| Quartile 4 | 12265 (24.1) | 2448 (24) | 4802 (25.4) | 958 (25.4) | 8244 (21.6) | 1669 (21.9) | 6594 (20.4) | 1357 (21) | 5814 (19.9) | 1194 (20.4) | 4138 (18.2) | 835 (18.3) | |
|
| |||||||||||||
| Number of outpatient visits (Quartile) |
Quartile 1
|
5633 (11.1) | 1099 (10.8) | 1968 (10.4) | 390 (10.3) | 2977 (7.8) | 621 (8.1) | 2513 (7.8) | 525 (8.1) | 2359 (8.1) | 490 (8.4) | 1677 (7.4) | 360 (7.9) |
|
Quartile 2
|
13750 (27) | 2717 (26.7) | 3279 (17.4) | 662 (17.5) | 6574 (17.2) | 1325 (17.4) | 5391 (16.7) | 1056 (16.3) | 4850 (16.6) | 974 (16.6) | 4116 (18.1) | 821 (18) | |
|
Quartile 3
|
11074 (21.8) | 2173 (21.3) | 5542 (29.3) | 1120 (29.6) | 9539 (25) | 1881 (24.6) | 8000 (24.7) | 1593 (24.6) | 7607 (26) | 1544 (26.4) | 6477 (28.4) | 1275 (28) | |
| Quartile 4 | 20468 (40.2) | 4196 (41.2) | 8106 (42.9) | 1607 (42.5) | 19090 (50) | 3809 (49.9) | 16471 (50.9) | 3301 (51) | 14479 (49.4) | 2851 (48.7) | 10525 (46.2) | 2103 (46.1) | |
|
| |||||||||||||
| Total number of inpatient stays including the birth admission (n) |
0
|
0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
|
1
|
46873 (92) | 9335 (91.7) | 15503 (82.1) | 3055 (80.8) | 29057 (76.1) | 5755 (75.4) | 23711 (73.2) | 4674 (72.2) | 21020 (71.8) | 4140 (70.7) | 15990 (70.2) | 3161 (69.3) | |
|
2
|
3412 (6.7) | 712 (7) | 2668 (14.1) | 561 (14.9) | 6503 (17) | 1320 (17.3) | 6164 (19) | 1259 (19.4) | 5573 (19) | 1152 (19.7) | 4464 (19.6) | 921 (20.2) | |
| 3 or more | 640 (1.3) | 138 (1.4) | 724 (3.8) | 163 (4.3) | 2620 (6.9) | 561 (7.4) | 2500 (7.7) | 542 (8.4) | 2702 (9.2) | 567 (9.7) | 2341 (10.3) | 477 (10.5) | |
|
| |||||||||||||
| <36 weeks gestational age |
No
|
45241 (88.8) | 9045 (88.8) | 16435 (87) | 3258 (86.2) | 34795 (91.1) | 6906 (90.4) | 30606 (94.5) | 6095 (94.1) | 27798 (94.9) | 5541 (94.6) | 21887 (96) | 4366 (95.8) |
| Yes | 5684 (11.2) | 1140 (11.2) | 2460 (13) | 521 (13.8) | 3385 (8.9) | 730 (9.6) | 1769 (5.5) | 380 (5.9) | 1497 (5.1) | 318 (5.4) | 908 (4) | 193 (4.2) | |
|
| |||||||||||||
| Low birth weight (<2500g and ≥1500g) |
No
|
46312 (90.9) | 9298 (91.3) | 16820 (89) | 3369 (89.2) | 35374 (92.7) | 7048 (92.3) | 30790 (95.1) | 6130 (94.7) | 27874 (95.2) | 5569 (95.1) | 21778 (95.5) | 4342 (95.2) |
| Yes | 4613 (9.1) | 887 (8.7) | 2075 (11) | 410 (10.9) | 2806 (7.4) | 588 (7.7) | 1585 (4.9) | 345 (5.3) | 1421 (4.9) | 290 (5) | 1017 (4.5) | 217 (4.8) | |
|
| |||||||||||||
| Very low birth weight (<1500g and ≥1000g) |
No
|
49599 (97.4) | 9886 (97.1) | 18411 (97.4) | 3669 (97.1) | 37663 (98.7) | 7522 (98.5) | 32046 (99) | 6405 (98.9) | 29037 (99.1) | 5806 (99.1) | 22592 (99.1) | 4519 (99.1) |
| Yes | 1326 (2.6) | 299 (2.9) | 484 (2.6) | 110 (2.9) | 517 (1.4) | 114 (1.5) | 329 (1) | 70 (1.1) | 258 (0.9) | 53 (0.9) | 203 (0.9) | 40 (0.9) | |
|
| |||||||||||||
| Extremely low birth weight (<1000g) |
No
|
50444 (99.1) | 10058 (98.8) | 18618 (98.5) | 3714 (98.3) | 37934 (99.4) | 7578 (99.2) | 32251 (99.6) | 6447 (99.6) | 29130 (99.4) | 5825 (99.4) | 22691 (99.5) | 4538 (99.5) |
| Yes | 481 (0.9) | 127 (1.3) | 277 (1.5) | 65 (1.7) | 246 (0.6) | 58 (0.8) | 124 (0.4) | 28 (0.4) | 165 (0.6) | 34 (0.6) | 104 (0.5) | 21 (0.5) | |
|
| |||||||||||||
| Endocrine, nutritional, metabolic, and immunity disorders (Chronic) |
No
|
49707 (97.6) | 9919 (97.4) | 18251 (96.6) | 3632 (96.1) | 36622 (95.9) | 7294 (95.5) | 30851 (95.3) | 6129 (94.7) | 27742 (94.7) | 5524 (94.3) | 21463 (94.2) | 4279 (93.9) |
| Yes | 1218 (2.4) | 266 (2.6) | 644 (3.4) | 147 (3.9) | 1558 (4.1) | 342 (4.5) | 1524 (4.7) | 346 (5.3) | 1553 (5.3) | 335 (5.7) | 1332 (5.8) | 280 (6.1) | |
|
| |||||||||||||
| Diseases of blood and blood-forming organs (Chronic) |
No
|
50422 (99) | 10073 (98.9) | 18477 (97.8) | 3684 (97.5) | 36955 (96.8) | 7351 (96.3) | 31054 (95.9) | 6196 (95.7) | 27941 (95.4) | 5585 (95.3) | 21642 (94.9) | 4321 (94.8) |
| Yes | 503 (1) | 112 (1.1) | 418 (2.2) | 95 (2.5) | 1225 (3.2) | 285 (3.7) | 1321 (4.1) | 279 (4.3) | 1354 (4.6) | 274 (4.7) | 1153 (5.1) | 238 (5.2) | |
|
| |||||||||||||
| Diseases of the nervous system and sense organs (Chronic) |
No
|
48485 (95.2) | 9647 (94.7) | 16597 (87.8) | 3315 (87.7) | 28135 (73.7) | 5605 (73.4) | 23373 (72.2) | 4635 (71.6) | 21560 (73.6) | 4280 (73.1) | 16521 (72.5) | 3261 (71.5) |
| Yes | 2440 (4.8) | 538 (5.3) | 2298 (12.2) | 464 (12.3) | 10045 (26.3) | 2031 (26.6) | 9002 (27.8) | 1840 (28.4) | 7735 (26.4) | 1579 (27) | 6274 (27.5) | 1298 (28.5) | |
|
| |||||||||||||
| Diseases of the circulatory system (Chronic) |
No
|
49985 (98.2) | 9972 (97.9) | 18270 (96.7) | 3640 (96.3) | 36901 (96.7) | 7364 (96.4) | 31256 (96.5) | 6242 (96.4) | 28177 (96.2) | 5621 (95.9) | 21907 (96.1) | 4367 (95.8) |
| Yes | 940 (1.9) | 213 (2.1) | 625 (3.3) | 139 (3.7) | 1279 (3.4) | 272 (3.6) | 1119 (3.5) | 233 (3.6) | 1118 (3.8) | 238 (4.1) | 888 (3.9) | 192 (4.2) | |
|
| |||||||||||||
| Diseases of the respiratory system (Chronic) |
No
|
49424 (97.1) | 9853 (96.7) | 15320 (81.1) | 3071 (81.3) | 23683 (62) | 4718 (61.8) | 15204 (47) | 3070 (47.4) | 11954 (40.8) | 2404 (41) | 8406 (36.9) | 1718 (37.7) |
| Yes | 1501 (3) | 332 (3.3) | 3575 (18.9) | 708 (18.7) | 14497 (38) | 2918 (38.2) | 17171 (53) | 3405 (52.6) | 17341 (59.2) | 3455 (59) | 14389 (63.1) | 2841 (62.3) | |
|
| |||||||||||||
| Diseases of the digestive system (Chronic) |
No
|
45600 (89.5) | 9092 (89.3) | 16449 (87.1) | 3266 (86.4) | 32625 (85.5) | 6479 (84.9) | 28043 (86.6) | 5570 (86) | 25752 (87.9) | 5120 (87.4) | 20324 (89.2) | 4024 (88.3) |
| Yes | 5325 (10.5) | 1093 (10.7) | 2446 (13) | 513 (13.6) | 5555 (14.6) | 1157 (15.2) | 4332 (13.4) | 905 (14) | 3543 (12.1) | 739 (12.6) | 2471 (10.8) | 535 (11.7) | |
*
This table contains aggregated summary data displaying representative variables. For the purposes of this table, children from Texas and New York were combined. Children from the >Birth – ≤28 days and >28 days – ≤6 months, >1 yr – ≤1.5 yrs and >1.5 yrs – ≤2 yrs, >2 yrs – ≤2.5 yrs and >2.5 yrs – ≤3 yrs, >3 yrs – ≤3.5 yrs and >3.5 yrs – ≤4 yrs, and >4 yrs – ≤4.5 yrs and >4.5yrs – ≤5 yrs categories were also combined. For state and procedure specific tables with non-aggregated age categories and all variables used, refer to Supplemental Content Tables 5–12.