Table 2.
Number of individuals with complete genotype and phenotype data (N), their mean age (SD), % male, allele/VNTR coding, minor allele frequency (MAF) and the P value of the test for Hardy-Weinberg Equilibrium (HWE).
| Gene | N | Age | Male | Minor allele | 0 | 1 | 2 | MAF | HWE |
|---|---|---|---|---|---|---|---|---|---|
| μ (SD) | % | Allele/repeat | Allele/repeat | Allele/repeat | |||||
| DRD1 (rs265981) | 10244 | 34.46 (16.00) | 38.8 | A | GG | AG | AA | .36 | .05 |
| DRD2/ANKK1 (rs1800497) | 10247 | 32.37 (15.98) | 39.5 | A | GG | AG | AA | .19 | .23 |
| DRD3 (rs6280) | 10247 | 32.46 (16.00) | 38.8 | C | TT | TC | CC | .31 | .36 |
| DBH (rs2519152) | 10245 | 32.46 (16.00) | 38.8 | C | CC | TC | TT | .47 | .43 |
| COMT (rs4680) | 10246 | 32.46 (16.00) | 38.8 | A | GG | AG | AA | .45 | .68 |
| DAT1 (VNTR 40bp) | 3586 | 27.78 (14.87) | 43.1 | 440bp | Two 480bp | 440bp – 480bp | Two 440 bp | .25 | .37 |
| DRD4 (VNTR 48bp) | 3363 | 28.61 (15.08) | 43.7 | 7r | No 7r | One 7r | Two 7r | .18 | .54 |
| DRD5 (VNTR 130–166bp) | 3680 | 28.60 (14.97) | 42.2 | 148bp | No 148bp | One 148bp | Two 148bp | .49 | .43 |
| MAOA (VNTR 30bp) | |||||||||
| - Males | 1564 | 29.38 (15.59) | - | >=3.5r | One <3.5r | - | One >=3.5r | .34 | n.a. |
| - Females | 2052 | 28.28 (14.55) | - | >=3.5r | Two <3.5r | <3.5r – >=3.5r | Two >=3.5r | .37 | .86 |