. Author manuscript; available in PMC: 2019 Mar 15.

Published in final edited form as: Cell Chem Biol. 2018 Jan 4;25(3):279–290.e7. doi: 10.1016/j.chembiol.2017.12.007

KEY RESOURCES TABLE.

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Bacterial strains
E.c. BL21	New England BioLabs	Cat# C2527I
E.c. BL21- CodonPlus (DE3)-RIL	Agilent Technologies	#230245

Fungal Strains
S.c. BY4743	OpenBiosyste ms	Cat# YSC1050
S.c. BY4743Δ8	Dominic Hoepfner’s lab	BY4743Δ8
S.c heterozygous, genome-wide deletion collection	OpenBiosyste ms	Cat# YSC1055
S.c homozygous, genome-wide deletion collection	OpenBiosyste ms	Cat# YSC1056
S.c. CTY1-1A	Bankaitis’ lab	CTY1-1A
S.c. CTY159	Bankaitis’ lab	CTY159
S.c. CTY303	Bankaitis’ lab	CTY303
C.albicans	American Type Culture Collection (ATCC)	Cat# 10231
C.glabrata	American Type Culture Collection (ATCC)	Cat# 2001
A.brasiliensis	American Type Culture Collection (ATCC)	Cat# 16404
C.neoformans	Royal Botanic Gardens, Kew	Cat# DSM70219

Mammalian Cell Lines
Human colorectoral carcinoma cell line HCT116	American Type Culture Collection (ATCC)	Cat# CCL-247

Recombinant DNA
Plasmid: SEC14_CG	Bankaitis’ lab	pDK247
Plasmid: SEC14_CA	Bankaitis’ lab	pDK9
Plasmid: SEC14_CA^{M154V, C154V}	Bankaitis’ lab	pDK265
Plasmid: pDR195-SEC14	Bankaitis’ lab	pDR195
Plasmid: YCplac33-SFH1	Schaaf’s lab	N/A
Plasmid: YCplac33- SFH1*	Schaaf’s lab	N/A
Plasmid: YCplac33- SEC14	Schaaf’s lab	N/A
Plasmid: BYInt	Hoepfner’s lab	pBYInt_LEU

Chemicals and Recombinant Proteins
Compounds 1- 48	Waldman’s lab	Compound number as listed in Table S1
His₈-Sec14	Schaaf’s lab	N/A
His₈-Sec14_Y151H	Bankaitis’ lab	N/A
His₈-Sec14_V154G	Bankaitis’ lab	N/A
His₈-Sec14_V155A	Bankaitis’ lab	N/A
His₈-Sec14_S173L	Bankaitis’ lab	N/A
His₈-Sec14_S201G	Bankaitis’ lab	N/A

Software and Algorithms
Tibco Spotfire	TIBCO Software Inc.	http://www.spotfire.tibco.com
GOLD Suite	The Cambridge Crystallographic Data Centre (CCDC)	https://www.ccdc.cam.ac.uk
Pymol	Schrödigner	https://pymol.org
XDS	Kabsch et al., Max-Plack Institute, Heidelberg	http://xds.mpimf-heidelberg.mpg.de
Phaser	McCoy et al., University of Cambridge	http://www.ccp4.ac.uk/html/phaser.html
Coot	Emsley et al., University of Cambridge	https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/
MOE	Chemical Computing Group	https://www.chemcomp.com/

Critical Commercial Assays
CellTiter-Glo Luminescent Cell Viability Assay	Promega	Cat# G7573

Deposited Data
S.c. Sec14::compound 2 co-crystal structure	Protein databank	PDB 6F0E (http://www.rcsb.org/pdb/explore/explore.do?structureId=6F0E)