Table 5.
Results of unadjusted and adjusted linear regression analyses that evaluated for differences in symptom severity and distress scores between premenopausal and postmenopausal women 12 months after surgery
| SYMPTOM | LINEAR REGRESSION RESULTS | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Symptom | Severity Score (0–10) Mean (SD) |
Covariate | Unadjusted Model | Adjusted Model | |||||
| Premen | Postmen | B | CI | p-value | B | CI | p-value | ||
| SYMPTOM SEVERITY | |||||||||
| Fatigue | 4.7 (2.6) | 3.8 (2.4) | Overall Model F=2.11; R2=.12; p=.027 |
||||||
| Menopausal status* | −0.73 | −1.51, 0.06 | .071 | −1.00 | −1.98, −0.01 | .048 | |||
| Age (in 5 year increments) | −0.15 | −0.36, 0.06 | .163 | ||||||
| Lives alone | 0.36 | −0.55, 1.27 | .437 | ||||||
| Working for pay | −0.58 | −1.35, 0.19 | .140 | ||||||
| SCQ score | 0.19 | 0.05, 0.34 | .008 | ||||||
| Prior HRT | 0.29 | −0.74, 1.31 | .580 | ||||||
| Any adjuvant chemotherapy in past 12 months | 0.40 | −0.42, 1.23 | .336 | ||||||
| Any adjuvant radiation therapy in past 12 months | 0.50 | −0.43, 1.44 | .290 | ||||||
| Any breast reconstructions months in past 12 months | −0.24 | −1.58, 1.11 | .729 | ||||||
| Type of surgery: lumpectomy (ref) vs mastectomy | −0.30 | −1.47, 0.88 | .616 | ||||||
| Impatience | 3.8 (2.3) | 2.7 (1.8) | Overall Model F=2.22; R2=.17; p=.022 |
||||||
| Menopausal status* | −1.15 | −1.88, −0.42 | .002 | −0.89 | −1.80, 0.02 | .055 | |||
| Age (in 5 year increments) | −0.12 | −0.30, 0.07 | .227 | ||||||
| Lives alone | −0.31 | −1.20, 0.58 | .486 | ||||||
| Working for pay | −0.18 | −0.92, 0.56 | .639 | ||||||
| SCQ score | 0.14 | −0.01, 0.29 | .061 | ||||||
| Prior HRT | −0.12 | −1.16, 0.92 | .816 | ||||||
| Any adjuvant chemotherapy in past 12 months | 0.66 | −0.11, 1.43 | .091 | ||||||
| Any adjuvant radiation therapy in past 12 months | 0.20 | −0.74, 1.14 | .678 | ||||||
| Any breast reconstructions months in past 12 months | 0.66 | −0.63, 1.95 | .313 | ||||||
| Type of surgery: lumpectomy (ref) vs mastectomy | −0.76 | −1.90, 0.39 | .194 | ||||||
| Irritability | 3.8 (2.4) | 2.9 (1.9) | Overall Model F=3.81; R2=.28; p<.001 |
||||||
| Menopausal status* | −1.10 | −1.91, −0.30 | .008 | −0.56 | −1.46, 0.34 | .219 | |||
| Age (in 5 year increments) | −0.32 | −0.52, −0.12 | .002 | ||||||
| Lives alone | 0.11 | −0.81, 1.03 | .814 | ||||||
| Working for pay | −0.31 | −1.09, 0.47 | .428 | ||||||
| SCQ score | 0.29 | 0.14, 0.45 | <.001 | ||||||
| Prior HRT | −0.08 | −1.17, 1.01 | .888 | ||||||
| Any adjuvant chemotherapy in past 12 months | 0.66 | −0.17, 1.48 | .119 | ||||||
| Any adjuvant radiation therapy in past 12 months | 0.26 | −0.70, 1.22 | .596 | ||||||
| Any breast reconstructions months in past 12 months | 0.86 | −0.45, 2.17 | .194 | ||||||
| Type of surgery: lumpectomy (ref) vs mastectomy | −0.32 | −1.4, 0.75 | .551 | ||||||
| SYMPTOM DISTRESS | |||||||||
| Symptom | Distress Score (0–10) Mean (SD) |
Covariate | Unadjusted Model | Adjusted Model | |||||
| PRE | POST | B | CI | p-value | B | CI | p-value | ||
| Impatience | 3.9 (2.9) | 2.6 (2.0) | Overall Model F=2.01; R2=.15; p=.039 |
||||||
| Menopausal status* | −1.29 | −2.17, −0.40 | .005 | −0.69 | −1.79, 0.41 | .217 | |||
| Age (in 5 year increments) | −0.18 | −0.42, 0.05 | .131 | ||||||
| Lives alone | −0.59 | −1.68, 0.50 | .283 | ||||||
| Working for pay | −0.28 | −1.18, 0.61 | .532 | ||||||
| SCQ score | 0.14 | −0.04, 0.32 | .134 | ||||||
| Prior HRT | −0.6 0 | −1.87, 0.68 | .354 | ||||||
| Any adjuvant chemotherapy in past 12 months | 0.53 | −0.41, 1.46 | .266 | ||||||
| Any adjuvant radiation therapy in past 12 months | −0.09 | −1.25, 1.08 | .884 | ||||||
| Any breast reconstructions months in past 12 months | 0.65 | −0.92, 2.22 | .413 | ||||||
| Type of surgery: lumpectomy (ref) vs mastectomy | −0.65 | −2.05, 0.75 | .36 0 | ||||||
Abbreviations: B = Beta coefficient; CI = confidence interval; HRT = hormone replacement therapy; Premen = premenopausal; Postmen = postmenopausal; ref = reference group; SCQ = Self-administered Comorbidity Questionnaire; vs = versus
*
reference group = premenopausal women