Table 2.

Summary of all toxicities Grade 2 and above attributed to study treatment.

	Gem Alone (before p53MVA) n=11			During p53MVA (possibly attributed to p53MVA or Gem) n=11			Gem Alone (after p53MVA) n=3
Adverse Event	Grade 2	Grade 3	Grade 4	Grade 2	Grade 3	Grade 4	Grade 2	Grade 3	Grade 4
Abdominal pain							1 (33%)
Allergic reaction	1 (9%)
Anemia	2 (18%)	2 (18%)		2 (18%)	3 (27%)
Back pain				1 (9%)
Creatinine increased				2 (18%)
Dyspnea				1 (9%)			1 (33%)
Edema				1 (9%)			1 (33%)
Fatigue	2 (18%)			4 (36%)			1 (33%)
Fever & Chills	2 (18%)
Headache				1 (9%)
Hypertension	1 (9%)			3 (27%)
Hypophosphatemia		1 (9%)		1 (9%)
Hypoxia				1 (9%)
Infection				1 (9%)
Injection site reaction				2 (18%)
Lymphocyte count decreased	1 (9%)	1 (9%)			1 (9%)
Nausea & Vomiting				1 (9%)
Neutrophil count decreased	1 (9%)	1 (9%)	1 (9%)	2 (18%)	3 (27%)			1 (33%)
Platelet count decreased	1 (9%)
Pleuritic pain							1 (33%)
Pneumonitis				1 (9%)
Rash maculo-papular	2 (18%)
Reversible posterior leukoencephalopathy				1 (9%)
Sore throat				1 (9%)