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Observed (symbols) and model predicted (lines) CDF amounts in control experiments following CDFDA dosing. A–C: apical compartment dosing; D–F: basolateral compartment dosing. A and D: apical compartment; B and E: cell compartment; C and F: basolateral compartment. The different lines in each figure represent the mean predicted CDF amount for a dosing occasion, and each symbol represents an individual filter, of which there were three for each occasion.
