A, Hemagglutinin inhibition (HAI) antibody titers and B, neutralizing antibody titers over time for critically ill adolescents and adults hospitalized with influenza A(H1N1)pdm09 virus infection — Canada, 2009–2011. Average curve was estimated among 25 survivors with ≥3 blood draws and at least one acute phase draw, collected ≤10 days after illness onset, using an unadjusted cubic linear mixed model. Individual lines are shown for all 47 enrolled patients with laboratory-confirmed influenza A(H1N1) pdm09 virus infection.