Table 3.

Demographic and Clinical Characteristics and Cause of Death for 9 Critically Ill Adolescents and Adults Who Died With 2009 Pandemic Influenza A(H1N1) Virus Infection—Canada, 2009–2011

Patient Age, Index	Time of Illness Onset	Sex	Age, y	PCR-Confirmed Infection	Seroconversion	Baseline Blood Sample			High-Risk Characteristic(s)	Time From Symptom Onset to Death, d	Clinical Comment(s)
						Time From Symptom Onset to Collection	HAI Ab Titer	Neutralizing Ab Titer
<65 y
1	Jun 2009	Female	17	Yes	No	9	226	160	Pregnant, First Nations race	28	Shock, ECMO use
2	Sep 2009	Female	40	Yes	No	3	160	5	First Nations race	17
3	Jun 2009	Male	42	Yes	Yes	7	28	5	Renal condition	16	Septic shock, renal failure, pneumonia, acute tension pneumothorax
4	Nov 2009	Female	47	No	Yes	8	63	28	Chronic lung condition, cardiovascular condition, renal condition, BMI ≥40,a diabetes mellitus, hematologic malignancy	34	Septic shock
≥65 y
5	Nov 2009	Female	65	No	Yes	8	20	5	Aged ≥65 y	16	Shock, pneumonia, acute lung injury
6	Nov 2009	Male	73	Yes	No	3	640	453	Aged ≥65 y, First Nations race, chronic lung condition, cardiovascular condition	28	Pneumonia
7	Nov 2009	Female	73	No	Yes	29	5	10	Aged ≥65 y	45	Malignancy
8	Nov 2009	Female	74	Yes	Yes	9	20	20	Aged ≥65 y, cardiovascular condition, renal condition, diabetes mellitus	19	Intracranial hemorrhage

Abbreviations: Ab, antibody; BMI, body mass index; ECMO, extracorporal membrane oxygenation; HAI, hemagglutinin inhibition; PCR, polymerase chain reaction.

^aBody mass index (BMI) is calculated as the weight in kilograms divided by the height in meters squared.