Skip to main content
. Author manuscript; available in PMC: 2019 Mar 16.
Published in final edited form as: Org Lett. 2018 Feb 23;20(6):1580–1583. doi: 10.1021/acs.orglett.8b00325

Scheme 2.

Scheme 2

Pd-Catalyzed C–O Cross-Coupling of Activated Aryl Halides with Primary Alcoholsa,b

aReaction conditions: ArX (1.0 mmol), n-BuOH (2.0 mmol), NaOt-Bu (1.2 mmol), P2 (1.0–2.0 mol %), 1,4-dioxane (1.0 mL, 1.0 M), rt–60 °C, 6–15 h. bThe reported isolated yields are average results of two runs.