Fig. 5.

sEPCR levels and hospital mortality. Soluble endothelial protein C receptor (sEPCR) was quantified in blood samples harvested at ICU admission (within the first 24 h). a Patients were categorized according to hospital mortality; ICU admission sEPCR levels were compared between survivors (N = 141) and non-survivors (N = 98). b Survivors and c non-survivors were further divided according to the presence of at least one H3 allele. Line in the box, median value; box edges, 25th to 75th centiles; whiskers, range of values. *p < 0.05, ***p < 0.001, ****p < 0.0001 with the Mann-Whitney test