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. 2018 Mar 16;8:4746. doi: 10.1038/s41598-018-23152-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Average network for each subgroup defined by hours of sleep (B) Weighted network with links that represent the differences among the subpopulation mean networks. (C) T_j-statistic as a function of the number of nodes in each subnetwork (j). The nodes identified by the minimum T_j are presented in the boxes, while the number of nodes identified by the procedure are represented with a red circle. (D) Nodes from the identified subnetwork are circled in blue. The nodes identified in (D) correspond to those in panel (B).