Table 3.
Relationship between thyroid hormone levels and DKD in total population.
| Characteristics | Groups | n | Model1 OR (95%CI) | P value | Model2 OR (95%CI) | P value |
|---|---|---|---|---|---|---|
| TSH | <2.5 | 577 | Reference | Reference | ||
| ≥2.50 | 285 | 1.044(0.763–1.428) | 0.789 | 0.804(0.551–1.173) | 0.258 | |
| FT3 | Q1(<4.38) | 209 | Reference | Reference | ||
| Q2(4.38 ≤ Q2<4.73) | 222 | 0.632(0.425–0.939) | 0.023 | 0.605(0.382–0.957) | 0.032 | |
| Q3(4.73 ≤ Q3<5.12) | 214 | 0.447(0.295–0.680) | <0.001 | 0.516(0.317–0.838) | 0.008 | |
| Q4(≥5.12) | 217 | 0.333(0.215–0.516) | <0.001 | 0.471(0.280–0.792) | 0.005 | |
| FT4 | Q1(<14.84) | 215 | Reference | Reference | ||
| Q2(14.84 ≤ Q2<16.13) | 215 | 0.958(0.637–1.440) | 0.835 | 1.005(0.627–1.610) | 0.984 | |
| Q3(16.13 ≤ Q3<17.66) | 212 | 0.703(0.459–1.075) | 0.103 | 0.668(0.410–1.089) | 0.105 | |
| Q4(≥17.66) | 220 | 0.811(0.536–1.225) | 0.319 | 1.066(0.657–1.729) | 0.797 | |
| TPO | <78 | 793 | Reference | Reference | ||
| ≥78 | 69 | 1.104(0.646–1.887) | 0.716 | 0.982(0.523–1.846) | 0.956 |
Model1: unadjusted Model2: adjusted for age, gender, duration of T2DM, BMI, smoking, hypertension, ARB/ACEI medication, insulin medication, metformin medication, HbA1c, TG, TC.