Table 3.

Association of rs3904778 with adolescent idiopathic scoliosis in male.

Population	Study	Number of samples		RAF		P value	Odds ratio (95% CI)	Phet
		Case	Control	Case	Control
Japanese	Japanese 1	105	6,383	0.447	0.405	2.42 × 10−1	1.18 (0.89–1.19)
	Japanese 2	50	412	0.480	0.482	9.73 × 10−1	0.99 (0.66–1.50)
Chinese	Guangzhou	98	469	0.367	0.319	1.87 × 10−1	1.24 (0.90–1.71)
	Hong Kong	31	102	0.387	0.289	1.45 × 10−1	1.55 (0.86–2.81)
	East Asian combined	284	7,366			5.62 × 10−2	1.19 (1.00–1.43)	0.67
Caucasian	USA	201	3,124	0.798	0.780	5.96 × 10−1	1.08 (0.81–1.45)
	All combined	485	10,490			5.72 × 10−2	1.16 (1.00–1.35)	0.76

RAF: risk allele frequency, CI: confidence interval.