Table 1.
Study, antidepressants studied | Effect ratio | 95% CI | N | Adjustments/exclusions/stratification |
---|---|---|---|---|
Nordeng et al. (2012), SSRI | 0.67 | 0.29, 1.52 | 1747 | a, b, d, h, g, j, i, l |
Jensen et al. (2013), AD | 1.42 | 1.16, 1.73 | 3966 | c, d, f, g, o |
El Marroun et al. (2012), SSRI | 1.72 | 0.73, 4.07 | 669 | c, d, e, f, g, h, j, k, m |
Oberlander et al. (2006), non-PS SSRI | 1.05 | 0.87, 1.28 | 15,685 | f |
Oberlander et al. (2006), PS SSRI | 1.69 | 1.14, 2.52 | 1622 | c, f, p |
Estimates in bold are statistically significant. Effect ratio is on log odds scale. a. Maternal mental health pre-birth, b. maternal age, c. socio-economic status, d. smoking in pregnancy, e. alcohol in pregnancy, f. other psychoactive drug and/or medication use during pregnancy, g. sex of child, h. gestational age, i. illness/disease during pregnancy, j. parity, k. ethnicity, l. folic acid use, m. body mass index, o. calendar year of delivery, p. psychiatric-related health service use
PS propensity score-matched sample, SSRI selective serotonin reuptake inhibitors, AD antidepressant, CI confidence interval