Table 2.
Results for neonate behaviour
| Study, antidepressants studied | Child age at testing (weeks) | Outcome | Effect size | 95% CI | N | Adjustments/exclusions/stratification |
|---|---|---|---|---|---|---|
| Suri et al. (2011), NR (most exposures sertraline and fluoxetine) | 6–8 | 1a. Habituation | 0.81 | 0.14, 1.48 | 46 | g |
| 1b. Orientation | − 0.38 | − 1.03, 0.27 | 46 | g | ||
| 1c. Motor | − 0.43 | − 1.09, 0.22 | 46 | g | ||
| 1d. Defence | 0.19 | − 0.46, 0.84 | 46 | g | ||
| 1e. Range of state | − 0.11 | − 0.76, 0.54 | 46 | g | ||
| 1f. Regulation of state | 0.17 | − 0.48, 0.82 | 46 | g | ||
| 1g. Autonomic stability | − 0.27 | − 0.92, 0.38 | 46 | g | ||
| h. Reflexes | 0.30 | − 0.35, 0.95 | 46 | g |
Estimates in bold are statistically significant. a. Maternal mental health pre-birth, b. maternal mental health at some point after delivery, c. maternal age, d. socio-economic status, e. smoking in pregnancy, f. alcohol in pregnancy, g. other psychoactive drug and/or medication use during pregnancy, h. sex of child, i. gestational age, j. age of child at testing, k. APGAR scores, l. breastfeeding, m. problems during pregnancy, n. mother-child connection, o. postnatal difficulties, p. ethnicity, q. exposure window
NR not reported, CI confidence interval