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. 2017 Jun 26;57(4):491–503. doi: 10.1007/s40262-017-0568-7

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — SLCO1B1 c.521T>C and ABCG2 c.421C>A genotyped rosuvastatin pharmacokinetic time courses in Caucasian, Chinese, and Korean populations. Blue circles and lines represent data and simulations for the wild type (i.e., SLCO1B1 c.521TT or ABCG2 c.421CC). Red triangles and lines represent data and simulations for homogenous mutations (i.e., SLCO1B1 c.521CC or ABCG2 c.421AA). Shaded areas indicate 95% confidence intervals approximated with parameter values generated in Markov chain Monte Carlo (confidence intervals presented here are to visualize the numerical uncertainty associated with mean simulations, but not inter-individual or inter-study variability. The same implication applies to the following figures)