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. 2017 Jun 26;57(4):491–503. doi: 10.1007/s40262-017-0568-7

Fig. 3.

Fig. 3

SLCO1B1 c.521T>C genotyped repaglinide pharmacokinetic time courses in Caucasian and Chinese populations. Blue circles and lines represent data and simulations for the wild type (i.e., SLCO1B1 c.521TT). Red triangles and lines represent data and simulations for homogenous mutations (i.e., SLCO1B1 c.521CC). Caucasian data are from four independent clinical studies. Shaded areas indicate 95% confidence intervals approximated with parameter values generated in Markov chain Monte Carlo