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. 2017 Jun 26;57(4):491–503. doi: 10.1007/s40262-017-0568-7

Table 1.

Frequencies of BCRP c.421CC, c.421CA, and c.421AA, and OATP1B1 c.521TT, c.521TC, and c.521CC in Caucasian, Chinese, Japanese, and Korean populations

Ethnicity BCRP Sample size References
c.421CC c.421CA c.421AA
Caucasian 0.82 0.17 0.01 982 [7, 33, 34]
Chinese 0.43 0.45 0.12 115 [33, 35]
Japanese 0.50 0.41 0.09 244 [36, 37]
Korean 0.52 0.40 0.08 250 [31]
Ethnicity OATP1B1 Sample size References
c.521TT c.521TC 521CC
Caucasian 0.64 0.32 0.04 468 [38]
Chinese 0.85 0.14 <0.01 128 [13, 3841]
Japanese 0.69 0.30 0.01 120 [42]
Korean 0.78 0.21 0.01 200 [43]

BCRP breast cancer resistance protein, OATP organic anion transporting polypeptide