Table 3.
Functional, analytic, microbiologic, and radiological characteristics of subjects with asthma, with and without bronchiectasis
| Parameter | Whole group (n = 398) |
Asthma with bronchiectasis (n = 113) |
Asthma without bronchiectasis (n = 285) |
P value |
|---|---|---|---|---|
| FEV1, % Post-BD (m ± sd) | 80 ± 22.9 | 77 ± 22 | 81 ± 23 | 0.061 |
| FEV1, (ml) Post-BD (m ± sd) | 1989 ± 829 | 1792 ± 785 | 2066 ± 834 | 0.002 |
| FVC, % Post-BD (m ± sd) | 93 ± 20 | 90 ± 17 | 94 ± 20 | 0.054 |
| FVC, (ml) Post-BD (m ± sd) | 2790 ± 1022 | 2542 ± 963 | 2888 ± 1029 | 0.002 |
| FEV1/FVC ratio Post-BD (m ± sd) | 69 ± 11 | 68.9 ± 11 | 69.8 ± 11 | ns |
| Classification by FEV1% | ns | |||
| > 80%, n (%) | 189 (47.59) | 45 (39.8) | 144 (50.5) | |
| 50- < 80%, n (%) | 179 (45) | 56 (49.6) | 123 (43.2) | |
| < 50%, n (%) | 30 (7.5) | 12 (10.6) | 18 (6.3) | |
| FeNO, ppb (m ± sd) | 29.9 ± 29.9 | 23.9 ± 23 | 32.3 ± 32 | 0.039 |
| Eosinophils, cells/μL (m ± sd) | 310 ± 254 | 324 ± 288 | 304 ± 239 | ns |
| IgE, IU/mL (m ± sd) | 269 ± 541 | 205 ± 362 | 298 ± 609 | ns |
| Positive sputum culture, n (%) | 50 (24.2) | 22 (29.7) | 28 (21.1) | ns |
| Air trapping measured by HRCT, n (%) | 52 (13) | 25 (22.1) | 27 (9.5) | 0.002 |
Data are presented as n (number) and (%) for qualitative variables and mean (standard deviation) for quantitative variables; ns not significant, FEV1 Forced expiratory volume in one second, post-BD Post-bronchodilator, FVC Forced vital capacity, FeNO Fractional exhaled nitric oxide, ppb parts per billion