Table 1.
Growth on receptor-deficient cells and neutralization profiles of A24 Cruzeiro and O1 Manisa and their derivatives
| Virus isolate | Cell line | VNT | ||
|---|---|---|---|---|
| CHO-K1 | CHO677 | Serum titer | r1-value | |
| A24 Cruzeiro | 2.8 ± 0.2 | negative | 3.4 ± 0.2 | |
| A24–179 | 2.3 ± 0.3 | negative | 3.6 ± 0.2 | 1.05 |
| A24-2P | 4.0 ± 0.4 | 2.5 ± 0.6 | 3.5 ± 0.1 | 1.02 |
| O1 Manisa | 2.8 ± 0.1 | negative | 3.2 ± 0.1 | |
| O1–179 | 2.0 ± 0.1 | negative | 3.5 ± 0.2 | 1.09 |
| O1-2P | 1.9 ± 0.2 | negative | 3.4 ± 0.1 | 1.06 |
Values represent mean virus and neutralization titers and standard deviations, shown as log10 infectious or neutralizing doses per milliliter. The r1-value was calculated by dividing the neutralization titer against the adapted isolate by the neutralization titer against the original virus isolate