Table 3.

Half maximal inhibitory concentration (IC₅₀) and selectivity index (SI) on DENV2 replication of methanolic extracts at 60 and 85 °C and the T. officinale and U. dioica fractions obtained by silica gel chromatography

	IC50 (μg/ml)	CC50 (μg/ml)	SI
T. officinale (60 °C)	132.50 ± 3.25	968.38 ± 37.17	7.31
U. dioica (60 °C)	74.51 ± 1.70	702.50 ± 14.50	9.43
T. officinale (85 °C)	179.1 ± 6.56	891.92 ± 29.19	4.98
U. dioica (85 °C)	194.7 ± 3.63	669.15 ± 17.13	3.44
T. officinale F-09a	165.70 ± 3.85	925.45 ± 29.27	5.59
U. dioica F-07a	126.10 ± 2.80	758.25 ± 24.75	6.01

SI was calculated by the formula: CC₅₀/IC₅₀

^aFraction number obtained by chromatography