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. 2018 Mar 14;11:1385–1394. doi: 10.2147/OTT.S153798

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© 2018 Ma et al. This work is published and licensed by Dove Medical Press Limited

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Rhein inhibits the invasive activity of A498 and 786-O cells in vitro.

Notes: (A) Effect of Rhein on the invasive activity of A498 cells in vitro. (B) Effect of Rhein on the invasive activity of 786-O cells in vitro. Cells were seeded onto a Matrigel chamber in the absence or presence of Rhein (30 or 60 μM). Transwell invasion assays were performed as described in the Materials and Methods section at 24 or 48 h after treatment. The left panel showed the number of invaded cells, which was photographed by a microscope. The right panel showed the quantitative results. The values presented are the mean ± SD from three independent experiments. Magnification ×100. **P<0.01. ***P<0.001.