Table 2.
Age- and multivariate* adjusted geometric mean aMT6s levels (ng/mg) by selected characteristics
| Age-adjusted | Fully adjusted | |||
|---|---|---|---|---|
|
| ||||
| Characteristic | Category Definition |
N† | Geometric mean aMT6s, 95% confidence interval |
Geometric mean aMT6s, 95% confidence interval |
| Age, years** | 14 | 20 | 43.3 (31.8, 60.0) | 42.7 (30.3, 60.3) |
| 15 | 27 | 40.0 (30.8–50.9) | 44.9 (36.5, 55.2) | |
| 16 | 28 | 35.5 (30.0, 43.5) | 34.3 (27.7, 43.4) | |
| 17 | 17 | 46.0 (38.2, 55.3) | 50.0 (41.3, 60.6) | |
| 18 | 8 | 47.6 (31.2, 71.5) | 46.4 (31.4, 68.4) | |
| P for trend‡ | 0.743 | 0.809 | ||
| Gender | Male | 44 | 37.2 (30.2, 45.9) | 39.3 (32.4, 47.8) |
| Female | 55 | 43.8 (38.7, 49.7) | 44.7 (39.1, 51.1) | |
| P for difference | 0.182 | 0.283 | ||
| BMI, kg/m2 | <20 | 39 | 43.9 (36.3, 53.0) | 43.3 (35.4, 53.0) |
| 20–25 | 48 | 38.1 (32.1, 45.1) | 40.5 (35.2, 46.5) | |
| >25 | 13 | 43.7 (32.7, 58.5) | 42.7 (31.2, 58.4) | |
| P for trend‡ | 0.487 | 0.563 | ||
| Ethnicity | Caucasian | 67 | 43.0 (37.0, 50.0) | 42.9 (37.1, 49.7) |
| Non-Caucasian | 32 | 36.9 (30.7, 44.4) | 40.8 (34.6, 48.1) | |
| P for difference | 0.214 | 0.648 | ||
| Age at menarche, years§ | 9 | 1 | 39.8 (36.8, 43.1) | - |
| 10 | 4 | 20.4 (12.7, 33.0) | 18.3 (12.2, 29.1) | |
| 11 | 7 | 32.5 (24.1, 43.6) | 33.5 (25.0, 44.9) | |
| 12 | 16 | 51.3 (42.7, 61.6) | 51.9 (43.7, 61.4) | |
| 13 | 18 | 50.7 (42.0, 61.2) | 50.3 (41.6, 60.8) | |
| 14 | 7 | 50.9 (38.7, 66.9) | 52.9 (38.0, 73.6) | |
| P for trend‡ | 0.002 | 0.001 | ||
| Time since menarche, years**,§ | 1 | 5 | 61.2 (36.9, 101.4) | 58.9 (34.6, 100.3) |
| 2 | 12 | 55.5 (42.0, 73.3) | 58.1 (40.5, 83.4) | |
| 3 | 11 | 49.6 (39.7, 61.9) | 50.7 (41.5, 61.9) | |
| 4 | 10 | 38.3 (30.4, 48.2) | 39.8 (32.7, 48.4) | |
| ≥5 | 15 | 34.6 (26.2, 45.7) | 32.5 (23.2, 45.5) | |
| P for trend‡ | 0.017 | 0.024 | ||
| Oral contraceptive use§ | Yes | 5 | 65.0 (46.7, 90.5) | 65.6 (46.7, 92.3) |
| No | 50 | 43.1 (38.0, 49.0) | 43.6 (38.2, 49.7) | |
| P for difference | 0.025 | 0.032 | ||
| Tobacco use | Yes | 2 | 27.6 (19.3, 39.5) | 51.7 (37.4, 71.5) |
| No | 96 | 42.4 (37.87, 47.5) | 42.2 (37.5, 47.4) | |
| P for difference | 0.026 | 0.266 | ||
| Alcohol use, past 30 days | Yes | 18 | 33.4 (23.9, 46.7) | 33.2 (24.0, 50.3) |
| No | 70 | 44.7 (40.2, 49.8) | 44.9 (40.1, 50.3) | |
| P for difference | 0.096 | 0.072 | ||
| Physical activity, hours/week | <4 | 30 | 43.7 (35.2, 54.2) | 44.4 (35.1, 56.1) |
| ≥4 | 67 | 40.5 (35.6, 46.1) | 41.5 (36.5, 47.1) | |
| P for difference | 0.545 | 0.614 | ||
| Use of sleep aids | Yes | 8 | 48.2 (33.3, 69.9) | 50.4 (36.1, 70.4) |
| No | 92 | 40.4 (35.7, 45.6) | 41.7 (36.9, 47.1) | |
| P for difference | 0.366 | 0.290 | ||
*
Adjusted for: age, gender, ethnicity, BMI, smoking status (yes/no), alcohol consumption (yes/no), physical activity for 4 h/wk or more (yes/no)
†
Actual numbers of participants in analyses may vary due to missing covariates;
**
Not age-adjusted;
‡
Ptrend calculated by modeling variables continuously;
§
Females only