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. Author manuscript; available in PMC: 2018 Mar 18.
Published in final edited form as: Nat Protoc. 2017 Jan 19;12(2):355–371. doi: 10.1038/nprot.2016.172

Figure 1. Harvard Dispersion Dosimetry Protocol (HDDP).

Figure 1

A hybrid experimental and computational approach to determine accurate dosimetry for in vitro toxicology study. The methodology includes 3 major parts illustrated here: ENM dispersion preparation, characterization of the ENM dispersion (hydrodynamic diameter and effective density), and computational fate and transport modeling to determine dosimetry.