Figure 1. Maraviroc did not significantly influence the anti-nociceptive response to morphine in C57BL/6J mice.
Latency to tail withdrawal (% MPE ± SEM) among C57BL/6J mice (n = 5 / group) that were administered vehicle (p.o.; black circles) or maraviroc (62 mg/kg, p.o.; blue circles) prior to (A) morphine (5 mg/kg, s.c.), (B) morphine (10 mg/kg, s.c.), or (C) a cumulative morphine dosing regimen (2 – 16 mg/kg, s.c.).