Figure 1.
PRRSV broadly neutralizing activity in sow serum. (A) ORF5 phylogeny of diverse PRRSV isolates. Herd isolates from 2009 –2012 are marked with an asterisk. Viruses representing maximal PRRSV diversity used in neutralizing assays are marked with squares. (B) Comparative neutralizing activity of 10 sows against 3 diverse PRRSV strains. (C) Cumulative 50% neutralizing titers against 3 diverse PRRSV strains for the 10 individual animals. Positive control was a sow from another herd previously tested for neutralizing activity. (D) Sow 7 neutralizing activity in serum. In panels B, C and C the symbols are open squares, VR2332, gray squares, SDEU, and black squares, MN184.