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. Author manuscript; available in PMC: 2019 Mar 15.
Published in final edited form as: Virus Res. 2018 Feb 3;248:13–23. doi: 10.1016/j.virusres.2018.01.015

Figure 6.

Figure 6

Expected outcome from peptide competition with neutralizing targets. (A) Depiction of predicted outcome of peptides added to cells before addition of virus. If peptide(s) bind cellular CD163, mimicking virus binding, they will compete with virus in a dose-dependent manner to result in reduced infection with increasing concentration of peptide. (B) Predicted outcome of peptides added to serum prior to addition of virus and infection of cells. If peptides bind neutralizing antibodies, they will compete with virus in a dose-dependent manner for binding and make more virus available for infection, i.e. they will inhibit neutralizing activity and result in increased infection with increasing concentration of peptide.