Table 3. Significant Clusters in Statistical Analyses.

The table displays anatomical regions (Talairach atlas), Brodmann Areas, and Montreal Neurological Imaging (x, y, z) coordinates, as well as cluster size (k) and peak activation (t_peak). (a) Paired t-test (fasting > fed) for right and left caudate seed regions. (b) Regression of seed regions (right caudate, left caudate) and eigenvector centrality (EVC) on insulin sensitivity (S_I) covarying for body mass index. (c) Regression of dorsal anterior cingulate cluster connectivity on SI during fasting and fed states.

	Hemisphere	Region	Brodmann Area	x	y	z	k	tpeak
(a) t-test
Right Caudate	R	Inferior Frontal Gyrus, Anterior Insula	47, 38, 28	28	16	−22	350	6.17
	R	Medial Temporal Gyrus, Superior Temporal Gyrus	20, 22, 13, 38	54	8	−14	614	5.43
	L	Medial Frontal Gyrus, Anterior Cingulate Cortex	10, 11, 32	−8	60	−14	306	4.66
	L	Posterior Cingulate Cortex, Precuneus, Hippocampus, Parahippocampus	31, 30, 23, 29, 7	−16	−32	−8	827	5.89
Left Caudate	R	Posterior Cingulate Cortex, Precuneus	30, 23	2	−48	20	152	4.9
(b) Regression
Right Caudate	L	Putamen		−24	−2	4	300	4.31
Left Caudate	L	Putamen		−18	0	4	406	8.17
	R	Putamen		18	2	0	399	7.64
EVC	Bilateral	Anterior Cigulate, Medial Frontal Cortex	32, 6, 8, 24	26	2	46	852	5.77
(c) dACC
Connectivity
Fasting	R	Middle Temporal Gyrus, Cuneus, Middle Occipital Gyrus	39, 30, 19, 37, 22	36	−70	10	1166	6.46
	L	Middle Occipital Gyrus, Cuneus, Middle Temporal Gyrus	30, 17	−26	−64	2	674	7.02
Fed	L	Superior Frontal Gyrus, Medial Frontal Gyrus	9, 10, 32	−20	52	26	628	−5.60
	R	Postcentral Gyrus, Supramarginal Gyrus	1, 2, 3, 40	44	−34	44	769	8.24