Table 1.
Demographic and clinical information.
Controls (n = 58) | Cocaine users (n = 59) | p Value | |
---|---|---|---|
Age | 30.5 ± 8.1 | 31.4 ± 7.6 | n.s. |
IQ | 104.7 ± 9.0 | 100.2 ± 8.4 | 0.01 |
Childhood trauma—total score | 33.5 ± 7.5 | 42 ± 14 | |
Childhood trauma—number of maltreatment categories | <0.001 | ||
0 maltreatment categories | 77.6% (n = 45) | 37.3% (n = 22) | |
1 maltreatment categories | 10.3% (n = 6) | 33.9% (n = 20) | |
2 maltreatment categories | 12.1% (n = 7) | 13.6% (n = 8) | |
3 maltreatment categories | 0% | 11.9% (n = 7) | |
4 maltreatment categories | 0% | 0% | |
5 maltreatment categories | 0% | 3.4% (n = 2) | |
Childhood trauma—types maltreatment (moderate/severe) | |||
Emotional abuse | 3.4% (n = 2) | 16.9% (n = 10) | 0.029 |
Physical abuse | 1.7% (n = 1) | 5.1% (n = 3) | n.s. |
Sexual abuse | 1.7% (n = 1) | 13.6% (n = 8) | 0.017 |
Emotional neglect | 13.8% (n = 8) | 35.6% (n = 21) | 0.006 |
Physical neglect | 13.8% (n = 8) | 42.4 (n = 25) | 0.001 |
State anxiety (total score) | 28 ± 8 | 35 ± 16 | <0.001 |
State anxiety (prevalence of clinically significant symptoms) | 10.3% (n = 6) | 34% (n = 20) | |
Lifetime prevalence of anxiety disorder | 1.7% (n = 1) | 6.8% (n = 4) | |
Beck Depression Inventory | 2.75 ± 3.45 | 10.62 ± 6.97 | <0.001 |
Lifetime prevalence of major depressive disorder | 6.8% (n = 4) | 34.4% (n = 20) | <0.001 |
Weekly alcohol intake | 3 ± 5.5 | 20 ± 22.5 | |
Lifetime alcohol abuse or dependence (DSM-IV) | 0% | 32.2% (n = 19) | |
Cocaine use—g/month | – | 7.33 ± 6.08 | |
Cocaine use—days/month | – | 8.50 ± 5.67 | |
Cocaine use—duration (years) | – | 6.00 ± 12.00 | |
Cocaine use—age of onset | – | 19.00 ± 4.00 | |
Cocaine use severity | – | 18.4 ± 5.83 | |
Lifetime cocaine abuse or dependence (DSM-IV) | – | 93% (n = 56) | |
Desire for cocaine use questionnaire | |||
Desire | – | 2 ± 2 | |
Negative reinforcement | – | 2.5 ± 2 | |
(Loss of) control | – | 3.80 ± 1.51 | |
Weekly cannabis use | – | 38.9% (n = 23) | |
Lifetime cannabis abuse or dependence (DSM-IV) | – | 28.8% (n = 17) | |
MDMA use in the last 6 months | – | 49.1% (n = 29) | |
Lifetime MDMA/XTC abuse or dependence (DSM-IV) | – | 8.5% (n = 5) |