Table 3.

Differences in amygdala connectivity during the processing of cocaine and neutral cues (in cocaine users).

	Cluster size # voxels	Cluster p value	Voxelz value	Peak voxel MNI coordinates			Voxel region
Left amygdala
Neutral > cocaine	792	<0.001	4.95	−60	−24	−4	L Middle temporal gyrus
			4.07	−46	−18	−8	L Superior temporal gyrus
	570	<0.001	4.77	−30	22	−8	L Insula
			4.15	−52	18	2	L Inferior frontal gyrus
	880	<0.001	4.39	54	−16	−12	Right middle temporal gyrus
			4.36	60	−20	−4	R Superior temporal gyrus
	774	<0.001	4.13	56	18	6	R Inferior frontal gyrus
			3.72	44	18	2	R Insula
			3.31	60	6	10	R Rolandic operculum
	309	0.008	4.04	−58	−46	34	L Supramarginal gyrus
			3.98	−60	−48	38	L Inferior parietal gyrus
Cocaine > neutral	No significant clusters
Right amygdala
Neutral > cocaine	324	0.003	4.42	−28	24	−6	L Insula
			3.6	−44	26	−10	L Inferior frontal gyrus
	386	0.001	4.39	−48	−22	−8	L Middle temporal gyrus
	209	0.023	4.12	34	44	22	L Middle frontal gyrus
			3.27	22	52	24	R Superior frontal gyrus
			3.23	30	36	30	R Middle frontal gyrus
	195	0.03	4.04	−6	34	44	L Medial frontal gyrus
	324	0.003	3.63	6	42	40	R Medial frontal gyrus
Cocaine > neutral	No significant clusters

All results were p < 0.05, cluster level family-wise error corrected with an initial height threshold of p = 0.001 uncorrected.

There was no significant group by stimulus type interaction effect on functional connectivity.