Figure 2.
Illustration of fiber tractography in color-coded diffusion tensor imaging map. For fornix, we have seeded first ROI in subcallosal green fibers seen in axial slice where body and crus of fornix can be observed (A) and second and third ROIs are seeded in the mid and distal parts of crus (B) (35). For uncinate fasciculus (UF), we have seeded first ROI in the coronal section of temporal lobe and second ROI in the superomedial green projections fibers at the anterior commissure level (C) (34). For cingulum, we have seeded first ROI and second ROI in supracallosal green projection fibers anteriorly (D) and posteriorly (E). Third ROI was seeded in the green hippocampal cingulum fibers seen in the medial temporal lobe (F) (4). Once a fiber tract was reconstructed, its entire trajectory was verified on a slice-by-slice basis to compare with established anatomical landmarks described in the human brain neuroanatomy atlases (33).