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. 2018 Mar 14;8(3):e019280. doi: 10.1136/bmjopen-2017-019280

Table 1.

Existing reviews about psychological treatments for schizophrenia

Intervention Existing reviews RCT* Comparator
Acceptance and commitment therapy Ongoing Cochrane review42 TAU, pharmacological intervention and another psychosocial intervention
Adherence interventions Gray et al 43 6 TAU and didactic health education
Active comparisons (befriending, CBT, cognitive remediation, psychoeducation, social skills training, supportive counselling) Turner et al 10 48 Befriending, CBT, cognitive remediation, psychoeducation, social skills training, supportive counselling, family intervention, art therapy, body psychotherapy, occupational therapy and problem-solving therapy
Art therapy Ruddy and Milnes6 2 Standard care
Assertive community treatment Marshall and Lockwood44 20† TAU, hospital-based rehabilitation and case management
Befriending
Bibliotherapy
Body-oriented psychological therapy
Case management Dieterich et al 45 40† Assertive community treatment, assertive outreach model, case management model and standard community care
CBT Zimmermann et al (positive symptoms)9 15 Waiting-list, TAU or another therapeutic treatment
Jones et al 7 20 Active (psychoeducation, family intervention, supportive psychotherapy, supportive counselling, cognitive remediation) and non-active control treatments (recreation and support, social activities, befriending and non-specific counselling)
Jauhar et al 46 52 Waiting-list, TAU or an intervention designed to control for the non-specific effects of psychotherapy (recreation and support, group support, befriending, supportive counselling/therapy, social activity therapy and goal-focused supportive contact) or active treatments (cognitive remediation and psychoeducation)
Van der Gaag et al (individually tailored)47 18 Any control condition was accepted
Hazell et al (low intensity)48 8 TAU and supportive psychotherapy
Kennedy and Xyrichis (auditory hallucinations)49 2 Non-specialised therapy (focused on supportive interactions and social integration)
Cognitive remediation Cella et al 50 45 TAU, active control (eg, computer games) another active treatment (eg, CBT)
Dance therapy Ren and Xia51 1 Standard care plus supportive counselling
Family interventions Pitschel-Walz et al 52 25 TAU, patient intervention, other family interventions
Pharoah et al 53 25 TAU, discussion groups, psychoeducation, supportive psychotherapy, psychosocial support
Group psychotherapeutic treatments Orfanos et al 54 34 TAU and other groups (active discussion group, support group, counselling group, occupational therapy group or problem-solving discussion group)
IPT Roder et al 55 16 TAU, placebo-attention condition and other active treatments
Psychological and psychosocial interventions for negative symptoms in psychosis Lutgens et al 8 95 TAU and active comparator (including psychoeducation, supportive therapy and cognitive remediation)
Metacognitive training Eichner and Berna56 12 TAU, wait-list control, supportive therapy, newspaper discussion group, CogPack (=cognitive remediation)
Mindfulness Aust and Bradshaw57 11† Active control intervention (eg, befriending and progressive muscle relaxation) and TAU
Music therapy Geretsegger et al 58 18 Placebo defined as an alternative therapy designed to control for effects of the therapist’s attention; TAU or no treatment
Psychodynamic therapy Malmberg and Fenton59 4 Reality adaptive, supportive psychotherapy, hospital comparison, ataraxic drugs, electro convulsive therapy, Milieu therapy and individual versus group
Psychoeducation Pekkala and Merinder60 10 TAU, supportive psychotherapy, behavioural intervention and leisure-time group
Social skills training Almerie et al 61 13 TAU, structured activities, discussion group, interaction group, and no treatment control
Supportive therapy Buckley et al 62 24 Standard care, any other treatment (biological, psychological or social) such as medication, problem-solving therapy, psychoeducation, social skills training, CBT, family therapy or psychodynamic psychotherapy
Systemic therapy Pinquart et al 5 7 No treatment

*Number of RCTs on patients with schizophrenia.

†RCTs about patients with severe mental illness including schizophrenia.

CBT, cognitive–behavioural therapy; IPT, integrated psychological therapy; RCT, randomised controlled trial; TAU, treatment as usual.