Table 2.
Reference, country | N | Mean age (years) | Male participants (%) | Recruitment period (years) | Maximum follow-up period | Patient diagnosis | Medication |
Aronov et al,39 Russia | 392 | 61.4 | 73.5 | None specified | 1 year | AMI, stable angina, unstable angina or myocardial revascularisation. | Standard medical therapy: β-blocker, acetylsalicyclic acid or other antithrombotic drug, nitrate, ACE inhibitor. Some patients on lipid-lowering drugs. |
Belardinelli et al,32 Italy | 118 | 61 | 100 | None specified | 33 months | CAD including AMI. Successful PCI in one or two native epicardial coronary arteries only. | According to international accepted protocols: aspirin, ticlopidine, calcium antagonists and nitrates. |
Briffa et al,40 Australia | 113 | 47.5 | 89.5 | None specified | 1 year | Uncomplicated AMI or recovery from unstable angina. PCI, CABG, thrombolytic therapy. | Aspirin, antiarrhytmic agent, β-blocker, ACE inhibitor, calcium antagonist, long-acting nitrate and diuretic. |
Giallauria et al,33 Italy | 61 | 58.5 | 78.5 | None specified | 6 months | AMI and undergone primary or rescue PCI only. | Aspirin, β-blocker, ACE inhibitor, ARB and statin. |
Hambrecht et al,30 Germany | 101 | 56 | 87.3 | 1997–2001 | 1 year | Stable CAD defined by angina pectoralis and amenable to PCI. AMI patients excluded. | β-receptor antagonists, β-HMG-CoA reductase inhibitors, ACE inhibitor and acetylsalicyclic acid. |
Higgins et al,41 Australia | 105 | 60.8 | 81.3 | 1995–1997 | 51 weeks | Post-PCI patients only. No AMI 1-month preprocedure. | Reference to medical therapy, only breakdown for lipid-lowering medication. |
Houle et al,42 Canada | 65 | 51.5 | 100 | 2007–2008 | 12 months | Patients hospitalised for an ACS (unstable angina, non-ST-elevation or ST elevation MI). PCI, CABG or no revascularisation procedure. | Reference to medication in usual care group but no breakdown. |
Kovoor et al,43 Australia | 142 | 51.5 | 100 | None specified | 6 months | AMI only. Thrombolytic therapy, one patient in the exercise treatment group had primary angioplasty. | Aspirin, β-blocker, ACE inhibitor, calcium channel blockers, nitrates and cholesterol-lowering agents. |
Maddison et al,44 New Zealand | 171 | 59 | 20 | 2010–2012 | 24 weeks | Diagnosis of IHD (angina, MI, revascularisation, including angioplasty, stent or CABG). | No description. |
Maroto et al,34 Spain | 180 | 76.9 | 57.5 | (None specified) 2-year enrolment period | 10 years | AMI only. | Medication regimens employed in secondary prevention at discharge were clearly insufficient by standard criteria but currently meet Spanish and European guidelines. |
Munk et al,35 Norway | 40 | 56.4 | 84.8 | None specified | 6 months | Stable angina and unstable angina, post-PCI only. AMI patients excluded. | Aspirin, β-blocker, ACE inhibitor, ARB, statin and acetylsalicyclic acid. |
Mutwalli et al,45 Saudi Arabia | 49 | 69.7 | 100 | 2008–2010 | 6 months | Undergone CABG surgery. Unknown whether AMI patients included. | Participants received advice that focused on medications, no breakdown. |
Oerkild et al,36 Denmark | 40 | 63.5 | 0 | 2007–2008 | 12 months (mortality data after 5.5 years) | Recent coronary event defined as AMI, PCI, CABG or without invasive procedure. | β-blocker, antithrombotics, calcium antagonists, lipid-lowering agents and diuretics. |
Reid et al,46 Canada | 223 | 54.5 | 87.3 | 2004–2007 | 12 months | ACS including AMI, underwent successful PCI only. | Reference to a ‘descriptive summary in supplemental table’, no access. |
Santaularia et al,29 Spain | 85 | 59.6 | 84.7 | None specified | 12 months | AMI only, no evidence of revascularisation procedure. | Reference to cardiac medication but no breakdown |
Seki et al,47 Japan | 39 | 57.8 | 83.8 | None specified | NR | AMI, PCI or CABG. | Reference to ‘lipid-lowering drugs and other medications’, no breakdown. |
Toobert et al,48 USA | 25 | 64.5 | 0 | None specified | 24 months | CAD defined as atherosclerosis, AMI, PCI or CABG. | Antihypertensive and hypolipidaemic medications. |
Vestfold Heartcare Study Group,37 Norway | 197 | 64 | 75.8 | None specified | 2 years | AMI, unstable angina pectoris or after PCI or CABG. | Aspirin, β-blocker, statin, ACE inhibitor, calcium antagonist and warfarin. |
Wang et al,49 China | 160 | 67 | 63.5 | 2005–2007 | 6 months | AMI only. | Antiplatelet, nitrate, β-blocker, ACE inhibitor, calcium antagonist and statin. |
West et al,31 UK | 1813 | 51.9 | 93.9 | 1997–2000 | 7–9 years | AMI only. | Aspirin, β-blocker, ACE inhibitor, diuretic, long-acting nitrate/calcium channel blocker, statin and GTN. |
Yu et al,50 China | 269 | 56 | 83.9 | None specified | 2 years | Recent AMI, after elective PCI or thrombolytic therapy. | Antiplatelet, β-blocker, calcium channel blocker, nitrate, statin, ACE inhibitor and diuretic. |
Zwisler et al,38 Denmark | 446 | 55.5 | 72.1 | 2000–2003 | 1 year | AMI, angina pectoris or after PCI or CABG. | Antithrombotics, lipid-lowering drugs, β-blocker, calcium antagonists, ACE inhibitor, diuretic and long-acting nitrates. |
ACS, acute coronary syndrome; AMI, acute myocardial infarction; ARB, angiotensin receptor blockers; CABG, coronary artery bypass graft; CAD, coronary artery disease; GTN, glyceryl trinitrate; IHD, ischaemic heart disease; MI, myocardial infarction; PCI, percutaneous coronary intervention.