Skip to main content
. 2018 Mar 14;8(3):e019656. doi: 10.1136/bmjopen-2017-019656

Table 2.

Overview of participants, recruitment period, patient diagnosis and medical therapy

Reference, country N Mean age (years) Male participants (%) Recruitment period (years) Maximum follow-up period Patient diagnosis Medication
Aronov et al,39 Russia 392 61.4 73.5 None specified 1 year AMI, stable angina, unstable angina or myocardial revascularisation. Standard medical therapy: β-blocker, acetylsalicyclic acid or other antithrombotic drug, nitrate, ACE inhibitor. Some patients on lipid-lowering drugs.
Belardinelli et al,32 Italy 118 61 100 None specified 33 months CAD including AMI. Successful PCI in one or two native epicardial coronary arteries only. According to international accepted protocols: aspirin, ticlopidine, calcium antagonists and nitrates.
Briffa et al,40 Australia 113 47.5 89.5 None specified 1 year Uncomplicated AMI or recovery from unstable angina. PCI, CABG, thrombolytic therapy. Aspirin, antiarrhytmic agent, β-blocker, ACE inhibitor, calcium antagonist, long-acting nitrate and diuretic.
Giallauria et al,33 Italy 61 58.5 78.5 None specified 6 months AMI and undergone primary or rescue PCI only. Aspirin, β-blocker, ACE inhibitor, ARB and statin.
Hambrecht et al,30 Germany 101 56 87.3 1997–2001 1 year Stable CAD defined by angina pectoralis and amenable to PCI. AMI patients excluded. β-receptor antagonists, β-HMG-CoA reductase inhibitors, ACE inhibitor and acetylsalicyclic acid.
Higgins et al,41 Australia 105 60.8 81.3 1995–1997 51 weeks Post-PCI patients only. No AMI 1-month preprocedure. Reference to medical therapy, only breakdown for lipid-lowering medication.
Houle et al,42 Canada 65 51.5 100 2007–2008 12 months Patients hospitalised for an ACS (unstable angina, non-ST-elevation or ST elevation MI). PCI, CABG or no revascularisation procedure. Reference to medication in usual care group but no breakdown.
Kovoor et al,43 Australia 142 51.5 100 None specified 6 months AMI only. Thrombolytic therapy, one patient in the exercise treatment group had primary angioplasty. Aspirin, β-blocker, ACE inhibitor, calcium channel blockers, nitrates and cholesterol-lowering agents.
Maddison et al,44 New Zealand 171 59 20 2010–2012 24 weeks Diagnosis of IHD (angina, MI, revascularisation, including angioplasty, stent or CABG). No description.
Maroto et al,34 Spain 180 76.9 57.5 (None specified) 2-year enrolment period 10 years AMI only. Medication regimens employed in secondary prevention at discharge were clearly insufficient by standard criteria but currently meet Spanish and European guidelines.
Munk et al,35 Norway 40 56.4 84.8 None specified 6 months Stable angina and unstable angina, post-PCI only. AMI patients excluded. Aspirin, β-blocker, ACE inhibitor, ARB, statin and acetylsalicyclic acid.
Mutwalli et al,45 Saudi Arabia 49 69.7 100 2008–2010 6 months Undergone CABG surgery. Unknown whether AMI patients included. Participants received advice that focused on medications, no breakdown.
Oerkild et al,36 Denmark 40 63.5 0 2007–2008 12 months (mortality data after 5.5 years) Recent coronary event defined as AMI, PCI, CABG or without invasive procedure. β-blocker, antithrombotics, calcium antagonists, lipid-lowering agents and diuretics.
Reid et al,46 Canada 223 54.5 87.3 2004–2007 12 months ACS including AMI, underwent successful PCI only. Reference to a ‘descriptive summary in supplemental table’, no access.
Santaularia et al,29 Spain 85 59.6 84.7 None specified 12 months AMI only, no evidence of revascularisation procedure. Reference to cardiac medication but no breakdown
Seki et al,47 Japan 39 57.8 83.8 None specified NR AMI, PCI or CABG. Reference to ‘lipid-lowering drugs and other medications’, no breakdown.
Toobert et al,48 USA 25 64.5 0 None specified 24 months CAD defined as atherosclerosis, AMI, PCI or CABG. Antihypertensive and hypolipidaemic medications.
Vestfold Heartcare Study Group,37 Norway 197 64 75.8 None specified 2 years AMI, unstable angina pectoris or after PCI or CABG. Aspirin, β-blocker, statin, ACE inhibitor, calcium antagonist and warfarin.
Wang et al,49 China 160 67 63.5 2005–2007 6 months AMI only. Antiplatelet, nitrate, β-blocker, ACE inhibitor, calcium antagonist and statin.
West et al,31 UK 1813 51.9 93.9 1997–2000 7–9 years AMI only. Aspirin, β-blocker, ACE inhibitor, diuretic, long-acting nitrate/calcium channel blocker, statin and GTN.
Yu et al,50 China 269 56 83.9 None specified 2 years Recent AMI, after elective PCI or thrombolytic therapy. Antiplatelet, β-blocker, calcium channel blocker, nitrate, statin, ACE inhibitor and diuretic.
Zwisler et al,38 Denmark 446 55.5 72.1 2000–2003 1 year AMI, angina pectoris or after PCI or CABG. Antithrombotics, lipid-lowering drugs, β-blocker, calcium antagonists, ACE inhibitor, diuretic and long-acting nitrates.

ACS, acute coronary syndrome; AMI, acute myocardial infarction; ARB, angiotensin receptor blockers; CABG, coronary artery bypass graft; CAD, coronary artery disease; GTN, glyceryl trinitrate; IHD, ischaemic heart disease; MI, myocardial infarction; PCI, percutaneous coronary intervention.